THEMATIC
Exploiting virulence genes in bacteria to create new antibiotics, antibiotic alternatives, and vaccines.
CURRENT PROJECTS
Development of a new class of antibiotics from tomatoes:
ATP synthetase inhibitors from carbapenem resistant Enterobacteriaceae, Acinetobacter and MRSA.
Repurposing traditional antibiotics and broadening their spectrum of activity
by combination to bacterial siderophores.
Development of a multivalent peptide vaccine against bovine mastitis.
Molecular pathogenesis and interspecific interactions between Pseudomonas aeruginosa and
methicillin-resistant Staphylococcus aureus (MRSA) in cystic fibrosis patients.
KEY WORDS
Staphylococcus aureus, SARM, Pseudomonas aeruginosa, Acinetobacter baumannii, Escherichia coli, persistent infections , resistance to antibiotics, cystic fibrosis, bovine mastitis, pathogenesis, virulence, vaccines.