Park S, Jung D, O’Brien B, Ruffini J, Dussault F, Dube-Duquette A, Demontier D, Lucier J-F, Malouin F, Dufour S, Ronholm J (2022) Comparative genomic analysis of Staphylococcus aureus isolates associated with either bovine intramammary infections or human infections demonstrates the importance of restriction-modification systems in host adaptation. Microb Genom. 2022 Feb;8(2):000779. https://doi.org/10.1099/mgen.0.000779
Bennett S, Fliss I, Said LB, Malouin F, Lacasse P (2022) Efficacy of bacteriocin-based formula for reducing staphylococci, streptococci and total bacterial counts on teat skin of dairy cows. J Dairy Science May;105(5):4498-4507 https://doi.org/10.3168/jds.2021-21381. Epub 2022 Mar 26.
Brouillette E, Goetz C, Droppa-Almeida D, Chamberland S, Jacques M, Malouin F. (2022) ‘Secondary Staphylococcus aureus intramammary colonization is reduced by non-aureus staphylococci exoproducts’, Microbes and infection, doi: 10.1016/j.micinf.2021.104879.
Bennett S, Said LB, Lacasse P, Malouin F, Fliss I. (2021) Susceptibility to nisin, bactofencin, pediocin and reuterin of multidrug resistant Staphylococcus aureus, Streptococcus dysgalactiae and Streptococcus uberis causing bovine mastitis. Antibiotics (Basel). 2021 Nov 19;10(11):1418. https://doi.org/10.3390/antibiotics10111418
Demontier E, Dubé-Duquette A, Brouillette E, Larose A, Ster S, Lucier J-F, Rodrigue S, Park S, Jung D, Ruffini J, Ronholm J, Dufour S, Roy J-P, Ramanathan S, Malouin F. (2021) ‘Relative virulence of Staphylococcus aureus bovine mastitis strains representing the main Canadian spa types and Clonal Complexes as determined using in vitro and in vivo mastitis models’, Journal of Dairy Science, doi: 10.3168/jds.2020-19904.
Ster C, Allard M, Gravel JC, Boulanger S, Lacasse P, Malouin F. (2021) ‘Immune and experimental infection responses of dairy cows vaccinated with the combination of six Staphylococcus aureus proteins that are expressed during bovine intramammary infection and a triple adjuvant’, Veterinaty Immunology and Immunology, 10290. doi:10.1016/j.vetimm.2021.110290.
Doghri I, Cherifi T, Goetz C, Malouin F, Jacques M. Fravalo P. (2021) ‘Counteracting Bacterial Motility: A Promising Strategy to Narrow Listeria monocytogenes Biofilm in Food Processing Industry’, Frontiers in Microbiology, 12. p. 1357. doi: 10.3389/fmicb.2021.673484.
Carratalá JV, Brouillette E, Serna N, Sánchez-Chardi A, Sánchez JM, Villaverde A, Arris A, Garcia-Fruitós E, Ferrer-Miralles N, Malouin F. (2020) ‘In Vivo Bactericidal Efficacy of GWH1 Antimicrobial Peptide Displayed on Protein Nanoparticles, a Potential Alternative to Antibiotics’, Pharmaceutics, 12(12), p. 1217. doi: 10.3390/pharmaceutics12121217.
Betoudji F, Abd El Rahman T, Miller MJ, Ghosh M, Jacques M, Bouarab K, Malouin F. (2020) ‘A Siderophore Analog of Fimsbactin from Acinetobacter Hinders Growth of the Phytopathogen Pseudomonas syringae and Induces Systemic Priming of Immunity in Arabidopsis thaliana’, Pathogens, 9(10), p. 806. doi: 10.3390/pathogens9100806.
Normandin C, Malouin F, Marsault E. (2020) ‘Gram-Scale Synthesis of Tomatidine, a Steroid Alkaloid with Antibiotic Properties Against Persistent Forms of Staphylococcus aureus: Gram-Scale Synthesis of Tomatidine, a Steroid Alkaloid with Antibiotic Properties Against Persistent Forms of Staphylococcus aureus’, European Journal of Organic Chemistry, 2020(18), pp. 2693–2698. doi: 10.1002/ejoc.202000051.
Langlois, J-P, Millette G, Guay I, Dubé-Duquette A, Chamberland S, Jacques P-É, Rodrigue S, Bouarab K, Marsault E, Malouin F. (2020) ‘Bactericidal Activity of the Bacterial ATP Synthase Inhibitor Tomatidine and the Combination of Tomatidine and Aminoglycoside Against Persistent and Virulent Forms of Staphylococcus aureus’, Frontiers in Microbiology, 11. doi: 10.3389/fmicb.2020.00805.
Bernier-Lachance J, Arsenault J, Usongo V, Parent É, Labrie J, Jacques M, Malouin, F, Archambault M. (2020) ‘Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada’, PloS One, 15(1), p. e0227183. doi: 10.1371/journal.pone.0227183.
Mordmuang A, Brouillette E, Voravuthikunchai SP, Malouin F. (2019) ‘Evaluation of a Rhodomyrtus tomentosa ethanolic extract for its therapeutic potential on Staphylococcus aureus infections using in vitro and in vivo models of mastitis’, Veterinary Research, 50(1), p. 49. doi: 10.1186/s13567-019-0664-9.
Côté-Gravel J, Malouin, F. (2019) ‘Symposium review: Features of Staphylococcus aureus mastitis pathogenesis that guide vaccine development strategies’, Journal of Dairy Science, 102(5), pp. 4727–4740. doi: 10.3168/jds.2018-15272.
Pichette-Jolette S, Millette G, Demontier E, Bran-Barrera D, Cyrenne M, Ster C, Haine D, Keefe G, Malouin F, Roy JP. (2019) ‘Partial prediction of the duration and the clinical status of Staphylococcus aureus bovine intramammary infections based on the phenotypic and genotypic analysis of isolates’, Veterinary Microbiology, 228, pp. 188–195. doi: 10.1016/j.vetmic.2018.11.024.
Jeukens, J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault J-G, Allard C, Barbeau J, Cantin AM, Charette SJ, Déziel E, Malouin F, Milot J, Nguyen D, Popa C, Boyle B, Levesque RC. (2019) ‘The Pseudomonas aeruginosa Population among Cystic Fibrosis Patients in Quebec, Canada: a Disease Hot Spot without Known Epidemic Isolates’, Journal of Clinical Microbiology, 57(6). doi: 10.1128/JCM.02019-18.
Lacasse E, Brouillette E, Larose A, Parr T R, Rubio A, Malouin F. (2019) ‘In Vitro Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria’, Antimicrobial Agents and Chemotherapy, 63(4). doi: 10.1128/AAC.02181-18.
Kahn LH, Bergeron G, Bourassa MW, De Vegt B, Gill J, Gomes F, Malouin F, Opengart K, Ritter GD, Singer RS, Storrs C, Topp E. (2019) ‘From farm management to bacteriophage therapy: strategies to reduce antibiotic use in animal agriculture’, Annals of the New York Academy of Sciences, 1441(1), pp. 31–39. doi: 10.1111/nyas.14034.
Millette G, Langlois JP, Brouillette E, Frost EH, Cantin AM, Malouin F. (2019) ‘Despite Antagonism in vitro, Pseudomonas aeruginosa Enhances Staphylococcus aureus Colonization in a Murine Lung Infection Model’, Frontiers in Microbiology, 10, p. 2880. doi: 10.3389/fmicb.2019.02880.
Kahn LH, Bergeron G, Bourassa MW, De Vegt B, Gill J, Gomes F, Malouin F, Opengart K, Ritter GD, Singer RS, Storrs C, Topp E. (2019) ‘From farm management to bacteriophage therapy: strategies to reduce antibiotic use in animal agriculture’, Annals of the New York Academy of Sciences, 1441(1), pp. 31–39. doi: 10.1111/nyas.14034.
Côté-Gravel J, Brouillette E, Malouin F. (2019) ‘Vaccination with a live-attenuated small-colony variant improves the humoral and cell-mediated responses against Staphylococcus aureus’, PloS One, 14(12), p. e0227109. doi: 10.1371/journal.pone.0227109.
Jamali H, Barkema HW, Jacques M, Lavallée-Bourget E-M, Malouin F, Saini V, Stryhn H, Dufour S. (2018) ‘Invited review: Incidence, risk factors, and effects of clinical mastitis recurrence in dairy cows’, Journal of Dairy Science, 101(6), pp. 4729–4746. doi: 10.3168/jds.2017-13730.
Lamontagne Boulet M, Isabelle C, Guay I, Brouillette E, Langlois J-P, Jacques P-É, Rodrigue S, Brzezinski R, Beauregard PB, Bouarab K, Boyapelly K, Boudreault PL, Marsault E, Malouin F. (2018) ‘Tomatidine Is a Lead Antibiotic Molecule That Targets Staphylococcus aureus ATP Synthase Subunit C’, Antimicrobial Agents and Chemotherapy, 62(6), pp. e02197-17, /aac/62/6/e02197-17.atom. doi: 10.1128/AAC.02197-17.
Guay I, Boulanger S, Isabelle C, Brouillette E, Chagnon F, Bouarab K, Marsault E, Malouin F. (2018) ‘Tomatidine and analog FC04-100 possess bactericidal activities against Listeria, Bacillus and Staphylococcus spp’, BMC pharmacology & toxicology, 19(1), p. 7. doi: 10.1186/s40360-018-0197-2.
Goetz C, Tremblay YDN, Lamarche D, Blondeau A, Gaudreau AM, Labrie J, Malouin F, Jacques M. (2017) ‘Coagulase-negative staphylococci species affect biofilm formation of other coagulase-negative and coagulase-positive staphylococci’, Journal of Dairy Science, 100(8), pp. 6454–6464. doi: 10.3168/jds.2017-12629.
Rehman MA, Carrillo C, Malouin F, and Diarra MS. (2017) ‘Draft Whole-Genome Sequences of Multidrug-Resistant Escherichia coli O157:H7 Strains Isolated from Feedlot Cattle Treated with Growth-Promoting Agents’, Genome Announcements, 5(18). doi: 10.1128/genomeA.00284-17.
Ster C, Lebeau V, Leclerc J, Fugère A, Veh KA, Roy J-P, Malouin F. (2017) ‘In vitro antibiotic susceptibility and biofilm production of Staphylococcus aureus isolates recovered from bovine intramammary infections that persisted or not following extended therapies with cephapirin, pirlimycin or ceftiofur’, Veterinary Research, 48(1), p. 56. doi: 10.1186/s13567-017-0463-0.
Asli A, Brouillette E, Ster C, Ghinet MG, Brzezinski R, Lacasse P, Jacques M, Malouin F. (2017) ‘Antibiofilm and antibacterial effects of specific chitosan molecules on Staphylococcus aureus isolates associated with bovine mastitis’, PloS One, 12(5), p. e0176988. doi: 10.1371/journal.pone.0176988.
King AM, King DT, French S, Brouillette E, Asli A, Alexander JAN, Vuckovic M, Maiti SN, Parr TRJr, Brown ED, Malouin F Strynadka NCJ, Wright GD. (2016) ‘Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins’, ACS chemical biology, 11(4), pp. 864–868. doi: 10.1021/acschembio.5b00944.
Asli A, Brouillette E, Krause KM, Nichols WW, Malouin, F. (2016) ‘Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria’, Antimicrobial Agents and Chemotherapy, 60(2), pp. 752–756. doi: 10.1128/AAC.02102-15.
Goetz C, Dufour S, Archambault M, Malouin F, Jacques M. (2016) ‘intra-mammaires chez la vache laitière : une revue bibliographique’, Revue Méd. Vét., p. 14.
Côté-Gravel J, Brouillette E, Obradović N, Ster C, Talbot BG, Malouin F. (2016) ‘Characterization of a vraG Mutant in a Genetically Stable Staphylococcus aureus Small-Colony Variant and Preliminary Assessment for Use as a Live-Attenuated Vaccine against Intrammamary Infections’, PloS One, 11(11), p. e0166621. doi: 10.1371/journal.pone.0166621.
Boulanger S, Mitchell G, Bouarab K, Marsault É, Cantin A, Frost EH, Déziel E, Malouin F. (2015) ‘Bactericidal Effect of Tomatidine-Tobramycin Combination against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa Is Enhanced by Interspecific Small-Molecule Interactions’, Antimicrobial Agents and Chemotherapy, 59(12), pp. 7458–7464. doi: 10.1128/AAC.01711-15.
Daigle F, Lerat S, Bucca G, Sanssouci É, Smith CP, Malouin F, Beaulieu C. (2015) ‘A terD domain-encoding gene (SCO2368) is involved in calcium homeostasis and participates in calcium regulation of a DosR-like regulon in Streptomyces coelicolor’, Journal of Bacteriology, 197(5), pp. 913–923. doi: 10.1128/JB.02278-14.
Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S. Maaroufi H. Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, Camara M, Cantin A, Charette SJ, Dewar K, Déziel E, Grimwood K, Hancock RE, Harrison JJ, Heeb S., Jelsbak L, Jia B, Kenna DT, Kidd TJ, Klockgether J, Lam JS, Lamont IL, Lewenza S. Loman N, Malouin F, Manos J, McArthur AG, McKewown J, Milot J, Naghra H., Nguyen D, Pereira SK, Perron GG, Pirnay J-P, Rainey PB, Rousseau S, Santos PM, Stephenson A, Taylor V, Turton JF, Waglechner N, Williams P, Thrane SW, Wright GD, Brinkman FS, Tucker NP, Tümmler B, Winstanley C, Levesque RC. (2015) ‘Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium’, Frontiers in Microbiology, 6, p. 1036. doi: 10.3389/fmicb.2015.01036.
Klein RC, Fabres-Klein MH, de Oliveira LL, Feio RN, Malouin F, Ribon A de OB. (2015) ‘A C-type lectin from Bothrops jararacussu venom disrupts Staphylococcal biofilms’, PloS One, 10(3), p. e0120514. doi: 10.1371/journal.pone.0120514.
Veh KA, Klein RC, Ster C, Keefe G, Lacasse P, Scholl D, Roy J-P, Haine D, Dufour S, Talbot BG, Ribon AOB, Malouin F. (2015) ‘Genotypic and phenotypic characterization of Staphylococcus aureus causing persistent and nonpersistent subclinical bovine intramammary infections during lactation or the dry period’, Journal of Dairy Science, 98(1), pp. 155–168. doi: 10.3168/jds.2014-8044.
Chagnon F, Guay I, Bonin MA, Mitchell G, Bouarab K, Malouin F, Marsault E. (2014) ‘Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus’, European Journal of Medicinal Chemistry, 80, pp. 605–620. doi: 10.1016/j.ejmech.2013.11.019.
Diarra MS, Malouin F. (2014) ‘Antibiotics in Canadian poultry productions and anticipated alternatives’, Frontiers in Microbiology, 5, p. 282. doi: 10.3389/fmicb.2014.00282.
Fugère A, Lalonde Séguin D, Mitchell G, Déziel E, Dekimpe V, Cantin AM, Frost E, Malouin F. (2014) ‘Interspecific small molecule interactions between clinical isolates of Pseudomonas aeruginosa and Staphylococcus aureus from adult cystic fibrosis patients’, PloS One, 9(1), p. e86705. doi: 10.1371/journal.pone.0086705.
Gagnon H, Beauchemin S, Kwiatkowska A, Couture F, D’Anjou F, Levesque C, Dufour F, Roberge Desbiens A, Vaillancourt R, Bernard S, Desjardins R, Malouin F, Dory YL, Day R. (2014) ‘Optimization of Furin Inhibitors To Protect against the Activation of Influenza Hemagglutinin H5 and Shiga Toxin’, Journal of Medicinal Chemistry, 57(1), pp. 29–41. doi: 10.1021/jm400633d.
Simmons K, Rempel H, Block G, Forgetta V, Vaillancourt R, Malouin F, Topp E, Delaquis P, Diarra MS. (2014) ‘Duplex PCR methods for the molecular detection of Escherichia fergusonii isolates from broiler chickens’, Applied and Environmental Microbiology, 80(6), pp. 1941–1948. doi: 10.1128/AEM.04169-13.
Allard M, Ster C, Jacob CL, Scholl D, Diarra MS, Lacasse P, Malouin F. (2013) ‘The expression of a putative exotoxin and an ABC transporter during bovine intramammary infection contributes to the virulence of Staphylococcus aureus’, Veterinary Microbiology, 162(2–4), pp. 761–770. doi: 10.1016/j.vetmic.2012.09.029.
Diarra MS, Block G, Rempel H, Oomah BD, Harrison J, McCallum J, Boulanger S, Brouillette E, Gattuso M, Malouin F. (2013) ‘In vitro and in vivo antibacterial activities of cranberry press cake extracts alone or in combination with β-lactams against Staphylococcus aureus’, BMC complementary and alternative medicine, 13, p. 90. doi: 10.1186/1472-6882-13-90.
Fatima M, Rempel H, Kuang XT, Allen KJ, Cheng KM, Malouin F, Diarra MS. (2013) ‘Effect of 3’,5’-cyclic diguanylic acid in a broiler Clostridium perfringens infection model’, Poultry Science, 92(10), pp. 2644–2650. doi: 10.3382/ps.2013-03143.
Mitchell G, Fugère A, Pépin Gaudreau K, Brouillette E, Frost EH, Cantin AM, Malouin F. (2013) ‘SigB is a dominant regulator of virulence in Staphylococcus aureus small-colony variants’, PloS One, 8(5), p. e65018. doi: 10.1371/journal.pone.0065018.
Pariseau É, Massé DI, Masse L, Topp E, Burrus V., Malouin F. (2013) ‘Coagulation–flocculation pre-treatment of surface water used on dairy farms and evaluation of bacterial viability and gene transfer in treatment sludge’, Water Quality Research Journal, 48(2), pp. 111–120. doi: 10.2166/wqrjc.2013.140.
Ster C, Allard M, Boulanger S, Lamontagne Boulet M, Mulhbacher J, Lafontaine DA, Marsault É, Lacasse P, Malouin F. (2013) ‘Experimental treatment of Staphylococcus aureus bovine intramammary infection using a guanine riboswitch ligand analog’, Journal of Dairy Science, 96(2), pp. 1000–1008. doi: 10.3168/jds.2012-5890.
Forgetta V, Rempel H, Malouin F, Vaillancourt R, Topp E, Dewar K, Diarra MS. (2012) ‘Pathogenic and multidrug-resistant Escherichia fergusonii from broiler chicken’, Poultry Science, 91(2), pp. 512–525. doi: 10.3382/ps.2011-01738.
Mitchell G, Lafrance M, Boulanger S, Séguin DL, Guay I, Gattuso M, Marsault É, Bouarab K, Malouin F. (2012) ‘Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression’, The Journal of Antimicrobial Chemotherapy, 67(3), pp. 559–568. doi: 10.1093/jac/dkr510.
Bordeleau E, Fortier L-C, Malouin F, Burrus V. (2011) ‘c-di-GMP turn-over in Clostridium difficile is controlled by a plethora of diguanylate cyclases and phosphodiesterases’, PLoS genetics, 7(3), p. e1002039. doi: 10.1371/journal.pgen.1002039.
Mitchell, G., Grondin, G., et al. (2011) ‘Infection of polarized airway epithelial cells by normal and small-colony variant strains of Staphylococcus aureus is increased in cells with abnormal cystic fibrosis transmembrane conductance regulator function and is influenced by NF-κB’, Infection and Immunity, 79(9), pp. 3541–3551. doi: 10.1128/IAI.00078-11.
Mitchell G, Gattuso M, Grondin G, Marsault É, Bouarab K, Malouin F. (2011) ‘Tomatidine inhibits replication of Staphylococcus aureus small-colony variants in cystic fibrosis airway epithelial cells’, Antimicrobial Agents and Chemotherapy, 55(5), pp. 1937–1945. doi: 10.1128/AAC.01468-10.
Pruneau M, Mitchell G, Moisan H, Dumont-Blanchette E, Jacob CL, Malouin F. (2011) ‘Transcriptional analysis of antibiotic resistance and virulence genes in multiresistant hospital-acquired MRSA’, FEMS immunology and medical microbiology, 63(1), pp. 54–64. doi: 10.1111/j.1574-695X.2011.00830.x.
Ster C, Beaudoin F, Diarra MS, Jacques M, Malouin F, Lacasse P. (2010) ‘Evaluation of some Staphylococcus aureus iron-regulated proteins as vaccine targets’, Veterinary Immunology and Immunopathology, 136(3–4), pp. 311–318. doi: 10.1016/j.vetimm.2010.03.010.
Lefebvre B, Diarra MS, Fairbrother JM, Nadeau E, Dubois M, Malouin F. (2010) ‘Intestinal mucosa adherence and cytotoxicity of a sorbitol-fermenting, Shiga-toxin-negative Escherichia coli O157:NM isolate with an atypical type III secretion system’, Foodborne Pathogens and Disease, 7(8), pp. 985–990. doi: 10.1089/fpd.2009.0474.
Mitchell G, Brouillette E, Séguin DL, Asselin A-E, Jacob CL, Malouin F. (2010) ‘A role for sigma factor B in the emergence of Staphylococcus aureus small-colony variants and elevated biofilm production resulting from an exposure to aminoglycosides’, Microbial Pathogenesis, 48(1), pp. 18–27. doi: 10.1016/j.micpath.2009.10.003.
Mitchell G, Séguin DL, Asselin A-E, Déziel E, Cantin AM, Frost EH, Michaud S, Malouin F. (2010) ‘Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N-oxide’, BMC microbiology, 10, p. 33. doi: 10.1186/1471-2180-10-33.
Moisan H, Pruneau M, Malouin F. (2010) ‘Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae’, The Journal of Antimicrobial Chemotherapy, 65(4), pp. 713–716. doi: 10.1093/jac/dkp503.
Mulhbacher J, Brouillette E, Allard M, Fortier L-C, Malouin F, Lafontaine DA. (2010) ‘Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways’, PLoS pathogens, 6(4), p. e1000865. doi: 10.1371/journal.ppat.1000865.
Diarra MS, Giguère K, Malouin F, Lefebvre B, Bach S, Delaquis P, Aslam M, Ziebell KA, Roy G. (2009) ‘Genotype, serotype, and antibiotic resistance of sorbitol-negative Escherichia coli isolates from feedlot cattle’, Journal of Food Protection, 72(1), pp. 28–36. doi: 10.4315/0362-028x-72.1.28.
González-Lamothe R, Mitchell G, Gattuso M, Diarra MS, Malouin F, Bouarab K. (2009) ‘Plant antimicrobial agents and their effects on plant and human pathogens’, International Journal of Molecular Sciences, 10(8), pp. 3400–3419. doi: 10.3390/ijms10083400.
Lefebvre B, Gattuso M, Moisan H, Malouin F, Diarra MS. (2009) ‘Genotype comparison of sorbitol-negative Escherichia coli isolates from healthy broiler chickens from different commercial farms’, Poultry Science, 88(7), pp. 1474–1484. doi: 10.3382/ps.2008-00426.
Lefebvre B, Diarra MS, Vincent C, Moisan H, Malouin F. (2009) ‘Relative cytotoxicity of Escherichia coli O157:H7 isolates from beef cattle and humans’, Foodborne Pathogens and Disease, 6(3), pp. 357–364. doi: 10.1089/fpd.2008.0188.
Miller MJ, Zhu H, Xu Y, Wu C, Walz AJ, Vergne A, Roosenberg JM, Moraski G, Minnick AA, McKee-Dolence J, Hu J, Fennell K, Dolence EK, Dong L., Franzblau S, Malouin F, Möllmann U. (2009) ‘Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents’, Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine, 22(1), pp. 61–75. doi: 10.1007/s10534-008-9185-0.
LeThanh BV, Lebeau CJ, Messier S, Malouin F, Scholl D. (2008) ‘Epidemiologic association of Staphylococcus aureus virulence markers with intramammary infection chronicity’, Lam, T. J. G. M. (ed.) Mastitis control: From science to practice: Proceedings of international conference 30 september - 2 October 2008 The Hague, the Netherlands. The Netherlands: Wageningen Academic Publishers. Page 167-174. doi: 10.3920/978-90-8686-649-6.
Atalla H, Gyles C, Jacob CL, Moisan H, Malouin F, Mallard B. (2008) ‘Characterization of a Staphylococcus aureus small colony variant (SCV) associated with persistent bovine mastitis’, Foodborne Pathogens and Disease, 5(6), pp. 785–799. doi: 10.1089/fpd.2008.0110.
Lefebvre B, Diarra MS, Moisan H, Malouin, F. (2008) ‘Detection of virulence-associated genes in Escherichia coli O157 and non-O157 isolates from beef cattle, humans, and chickens’, Journal of Food Protection, 71(9), pp. 1774–1784. doi: 10.4315/0362-028x-71.9.1774.
Mitchell G, Lamontagne C-A, Brouillette E, Grondin G, Talbot BG, Grandbois M, Malouin F. (2008) ‘Staphylococcus aureus SigB activity promotes a strong fibronectin-bacterium interaction which may sustain host tissue colonization by small-colony variants isolated from cystic fibrosis patients’, Molecular Microbiology, 70(6), pp. 1540–1555. doi: 10.1111/j.1365-2958.2008.06511.x.
Boulanger D, Brouillette E, Jaspar F, Malouin F, Mainil J, Bureau F, Lekeux P. (2007) ‘Helenalin reduces Staphylococcus aureus infection in vitro and in vivo’, Veterinary Microbiology, 119(2–4), pp. 330–338. doi: 10.1016/j.vetmic.2006.08.020.
Karaolis DKR, Means TK, Yang D, Takahashi M, Yoshimura T, Muraille E, Philpott D, Schroeder JT, Hyodo M, Hayakawa Y, Talbot BG, Brouillette, Malouin F. (2007) ‘Bacterial c-di-GMP is an immunostimulatory molecule’, Journal of Immunology (Baltimore, Md.: 1950), 178(4), pp. 2171–2181. doi: 10.4049/jimmunol.178.4.2171.
Mitchell G, Lamontagne C-A, Lebel R, Grandbois M, Malouin F. (2007) ‘Single-molecule dynamic force spectroscopy of the fibronectin-heparin interaction’, Biochemical and Biophysical Research Communications, 364(3), pp. 595–600. doi: 10.1016/j.bbrc.2007.10.034.
Allard M, Moisan H, Brouillette E, Gervais AL, Jacques M, Lacasse P, Diarra MS, Malouin F. (2006) ‘Transcriptional modulation of some Staphylococcus aureus iron-regulated genes during growth in vitro and in a tissue cage model in vivo’, Microbes and Infection, 8(7), pp. 1679–1690. doi: 10.1016/j.micinf.2006.01.022.
Lefebvre B, Malouin F, Roy G, Giguère K, Diarra MS. (2006) ‘Growth performance and shedding of some pathogenic bacteria in feedlot cattle treated with different growth-promoting agents’, Journal of Food Protection, 69(6), pp. 1256–1264. doi: 10.4315/0362-028x-69.6.1256.
Moisan H, Brouillette E, Jacob CL, Langlois-Bégin P, Michaud S, Malouin F. (2006) ‘Transcription of virulence factors in Staphylococcus aureus small-colony variants isolated from cystic fibrosis patients is influenced by SigB’, Journal of Bacteriology, 188(1), pp. 64–76. doi: 10.1128/JB.188.1.64-76.2006.
Bernier G, Girijavallabhan V, Murray A, Niyaz N, Ding P, Miller MJ, Malouin F. (2005) ‘Desketoneoenactin-siderophore conjugates for Candida: evidence of iron transport-dependent species selectivity’, Antimicrobial Agents and Chemotherapy, 49(1), pp. 241–248. doi: 10.1128/AAC.49.1.241-248.2005.
Brouillette E, Hyodo M, Hayakawa Y, Karaolis DKR, Malouin F. (2005) ‘3’,5’-cyclic diguanylic acid reduces the virulence of biofilm-forming Staphylococcus aureus strains in a mouse model of mastitis infection’, Antimicrobial Agents and Chemotherapy, 49(8), pp. 3109–3113. doi: 10.1128/AAC.49.8.3109-3113.2005.
Brouillette E, Grondin G, Talbo, BG, Malouin F. (2005) ‘Inflammatory cell infiltration as an indicator of Staphylococcus aureus infection and therapeutic efficacy in experimental mouse mastitis’, Veterinary Immunology and Immunopathology, 104(3–4), pp. 163–169. doi: 10.1016/j.vetimm.2004.11.006.
Brouillette E, Malouin F. (2005) ‘The pathogenesis and control of Staphylococcus aureus-induced mastitis: study models in the mouse’, Microbes and Infection, 7(3), pp. 560–568. doi: 10.1016/j.micinf.2004.11.008.
Lefebvre B, Diarra MS, Giguère K, Roy G, Michaud S, Malouin F. (2005) ‘Antibiotic resistance and hypermutability of Escherichia coli O157 from feedlot cattle treated with growth-promoting agents’, Journal of Food Protection, 68(11), pp. 2411–2419. doi: 10.4315/0362-028x-68.11.2411.
Malouin F, Brouillette E, Martinez A, Boyll BJ, Toth JL, Gage JL, Allen NE. (2005) ‘Identification of antimicrobial compounds active against intracellular Staphylococcus aureus’, FEMS immunology and medical microbiology, 45(2), pp. 245–252. doi: 10.1016/j.femsim.2005.04.003.
Brouillette E, Grondin G, Lefebvre C, Talbot B., Malouin F. (2004) ‘Mouse mastitis model of infection for antimicrobial compound efficacy studies against intracellular and extracellular forms of Staphylococcus aureus’, Veterinary Microbiology, 101(4), pp. 253–262. doi: 10.1016/j.vetmic.2004.04.008.
Brouillette E, Martinez A, Boyll BJ, Allen NE, Malouin, F. (2004) ‘Persistence of a Staphylococcus aureus small-colony variant under antibiotic pressure in vivo’, FEMS immunology and medical microbiology, 41(1), pp. 35–41. doi: 10.1016/j.femsim.2003.12.007.
Brouillette E, Talbot BG, Malouin F. (2003) ‘The fibronectin-binding proteins of Staphylococcus aureus may promote mammary gland colonization in a lactating mouse model of mastitis’, Infection and Immunity, 71(4), pp. 2292–2295. doi: 10.1128/iai.71.4.2292-2295.2003.
Bennett S, Fliss I, Said LB, Malouin F, Lacasse P (2022) Efficacy of bacteriocin-based formula for reducing staphylococci, streptococci and total bacterial counts on teat skin of dairy cows. J Dairy Science May;105(5):4498-4507 https://doi.org/10.3168/jds.2021-21381. Epub 2022 Mar 26.
Brouillette E, Goetz C, Droppa-Almeida D, Chamberland S, Jacques M, Malouin F. (2022) ‘Secondary Staphylococcus aureus intramammary colonization is reduced by non-aureus staphylococci exoproducts’, Microbes and infection, doi: 10.1016/j.micinf.2021.104879.
Bennett S, Said LB, Lacasse P, Malouin F, Fliss I. (2021) Susceptibility to nisin, bactofencin, pediocin and reuterin of multidrug resistant Staphylococcus aureus, Streptococcus dysgalactiae and Streptococcus uberis causing bovine mastitis. Antibiotics (Basel). 2021 Nov 19;10(11):1418. https://doi.org/10.3390/antibiotics10111418
Demontier E, Dubé-Duquette A, Brouillette E, Larose A, Ster S, Lucier J-F, Rodrigue S, Park S, Jung D, Ruffini J, Ronholm J, Dufour S, Roy J-P, Ramanathan S, Malouin F. (2021) ‘Relative virulence of Staphylococcus aureus bovine mastitis strains representing the main Canadian spa types and Clonal Complexes as determined using in vitro and in vivo mastitis models’, Journal of Dairy Science, doi: 10.3168/jds.2020-19904.
Ster C, Allard M, Gravel JC, Boulanger S, Lacasse P, Malouin F. (2021) ‘Immune and experimental infection responses of dairy cows vaccinated with the combination of six Staphylococcus aureus proteins that are expressed during bovine intramammary infection and a triple adjuvant’, Veterinaty Immunology and Immunology, 10290. doi:10.1016/j.vetimm.2021.110290.
Doghri I, Cherifi T, Goetz C, Malouin F, Jacques M. Fravalo P. (2021) ‘Counteracting Bacterial Motility: A Promising Strategy to Narrow Listeria monocytogenes Biofilm in Food Processing Industry’, Frontiers in Microbiology, 12. p. 1357. doi: 10.3389/fmicb.2021.673484.
Carratalá JV, Brouillette E, Serna N, Sánchez-Chardi A, Sánchez JM, Villaverde A, Arris A, Garcia-Fruitós E, Ferrer-Miralles N, Malouin F. (2020) ‘In Vivo Bactericidal Efficacy of GWH1 Antimicrobial Peptide Displayed on Protein Nanoparticles, a Potential Alternative to Antibiotics’, Pharmaceutics, 12(12), p. 1217. doi: 10.3390/pharmaceutics12121217.
Betoudji F, Abd El Rahman T, Miller MJ, Ghosh M, Jacques M, Bouarab K, Malouin F. (2020) ‘A Siderophore Analog of Fimsbactin from Acinetobacter Hinders Growth of the Phytopathogen Pseudomonas syringae and Induces Systemic Priming of Immunity in Arabidopsis thaliana’, Pathogens, 9(10), p. 806. doi: 10.3390/pathogens9100806.
Normandin C, Malouin F, Marsault E. (2020) ‘Gram-Scale Synthesis of Tomatidine, a Steroid Alkaloid with Antibiotic Properties Against Persistent Forms of Staphylococcus aureus: Gram-Scale Synthesis of Tomatidine, a Steroid Alkaloid with Antibiotic Properties Against Persistent Forms of Staphylococcus aureus’, European Journal of Organic Chemistry, 2020(18), pp. 2693–2698. doi: 10.1002/ejoc.202000051.
Langlois, J-P, Millette G, Guay I, Dubé-Duquette A, Chamberland S, Jacques P-É, Rodrigue S, Bouarab K, Marsault E, Malouin F. (2020) ‘Bactericidal Activity of the Bacterial ATP Synthase Inhibitor Tomatidine and the Combination of Tomatidine and Aminoglycoside Against Persistent and Virulent Forms of Staphylococcus aureus’, Frontiers in Microbiology, 11. doi: 10.3389/fmicb.2020.00805.
Bernier-Lachance J, Arsenault J, Usongo V, Parent É, Labrie J, Jacques M, Malouin, F, Archambault M. (2020) ‘Prevalence and characteristics of Livestock-Associated Methicillin-Resistant Staphylococcus aureus (LA-MRSA) isolated from chicken meat in the province of Quebec, Canada’, PloS One, 15(1), p. e0227183. doi: 10.1371/journal.pone.0227183.
Mordmuang A, Brouillette E, Voravuthikunchai SP, Malouin F. (2019) ‘Evaluation of a Rhodomyrtus tomentosa ethanolic extract for its therapeutic potential on Staphylococcus aureus infections using in vitro and in vivo models of mastitis’, Veterinary Research, 50(1), p. 49. doi: 10.1186/s13567-019-0664-9.
Côté-Gravel J, Malouin, F. (2019) ‘Symposium review: Features of Staphylococcus aureus mastitis pathogenesis that guide vaccine development strategies’, Journal of Dairy Science, 102(5), pp. 4727–4740. doi: 10.3168/jds.2018-15272.
Pichette-Jolette S, Millette G, Demontier E, Bran-Barrera D, Cyrenne M, Ster C, Haine D, Keefe G, Malouin F, Roy JP. (2019) ‘Partial prediction of the duration and the clinical status of Staphylococcus aureus bovine intramammary infections based on the phenotypic and genotypic analysis of isolates’, Veterinary Microbiology, 228, pp. 188–195. doi: 10.1016/j.vetmic.2018.11.024.
Jeukens, J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault J-G, Allard C, Barbeau J, Cantin AM, Charette SJ, Déziel E, Malouin F, Milot J, Nguyen D, Popa C, Boyle B, Levesque RC. (2019) ‘The Pseudomonas aeruginosa Population among Cystic Fibrosis Patients in Quebec, Canada: a Disease Hot Spot without Known Epidemic Isolates’, Journal of Clinical Microbiology, 57(6). doi: 10.1128/JCM.02019-18.
Lacasse E, Brouillette E, Larose A, Parr T R, Rubio A, Malouin F. (2019) ‘In Vitro Activity of Tebipenem (SPR859) against Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria’, Antimicrobial Agents and Chemotherapy, 63(4). doi: 10.1128/AAC.02181-18.
Kahn LH, Bergeron G, Bourassa MW, De Vegt B, Gill J, Gomes F, Malouin F, Opengart K, Ritter GD, Singer RS, Storrs C, Topp E. (2019) ‘From farm management to bacteriophage therapy: strategies to reduce antibiotic use in animal agriculture’, Annals of the New York Academy of Sciences, 1441(1), pp. 31–39. doi: 10.1111/nyas.14034.
Millette G, Langlois JP, Brouillette E, Frost EH, Cantin AM, Malouin F. (2019) ‘Despite Antagonism in vitro, Pseudomonas aeruginosa Enhances Staphylococcus aureus Colonization in a Murine Lung Infection Model’, Frontiers in Microbiology, 10, p. 2880. doi: 10.3389/fmicb.2019.02880.
Kahn LH, Bergeron G, Bourassa MW, De Vegt B, Gill J, Gomes F, Malouin F, Opengart K, Ritter GD, Singer RS, Storrs C, Topp E. (2019) ‘From farm management to bacteriophage therapy: strategies to reduce antibiotic use in animal agriculture’, Annals of the New York Academy of Sciences, 1441(1), pp. 31–39. doi: 10.1111/nyas.14034.
Côté-Gravel J, Brouillette E, Malouin F. (2019) ‘Vaccination with a live-attenuated small-colony variant improves the humoral and cell-mediated responses against Staphylococcus aureus’, PloS One, 14(12), p. e0227109. doi: 10.1371/journal.pone.0227109.
Jamali H, Barkema HW, Jacques M, Lavallée-Bourget E-M, Malouin F, Saini V, Stryhn H, Dufour S. (2018) ‘Invited review: Incidence, risk factors, and effects of clinical mastitis recurrence in dairy cows’, Journal of Dairy Science, 101(6), pp. 4729–4746. doi: 10.3168/jds.2017-13730.
Lamontagne Boulet M, Isabelle C, Guay I, Brouillette E, Langlois J-P, Jacques P-É, Rodrigue S, Brzezinski R, Beauregard PB, Bouarab K, Boyapelly K, Boudreault PL, Marsault E, Malouin F. (2018) ‘Tomatidine Is a Lead Antibiotic Molecule That Targets Staphylococcus aureus ATP Synthase Subunit C’, Antimicrobial Agents and Chemotherapy, 62(6), pp. e02197-17, /aac/62/6/e02197-17.atom. doi: 10.1128/AAC.02197-17.
Guay I, Boulanger S, Isabelle C, Brouillette E, Chagnon F, Bouarab K, Marsault E, Malouin F. (2018) ‘Tomatidine and analog FC04-100 possess bactericidal activities against Listeria, Bacillus and Staphylococcus spp’, BMC pharmacology & toxicology, 19(1), p. 7. doi: 10.1186/s40360-018-0197-2.
Goetz C, Tremblay YDN, Lamarche D, Blondeau A, Gaudreau AM, Labrie J, Malouin F, Jacques M. (2017) ‘Coagulase-negative staphylococci species affect biofilm formation of other coagulase-negative and coagulase-positive staphylococci’, Journal of Dairy Science, 100(8), pp. 6454–6464. doi: 10.3168/jds.2017-12629.
Rehman MA, Carrillo C, Malouin F, and Diarra MS. (2017) ‘Draft Whole-Genome Sequences of Multidrug-Resistant Escherichia coli O157:H7 Strains Isolated from Feedlot Cattle Treated with Growth-Promoting Agents’, Genome Announcements, 5(18). doi: 10.1128/genomeA.00284-17.
Ster C, Lebeau V, Leclerc J, Fugère A, Veh KA, Roy J-P, Malouin F. (2017) ‘In vitro antibiotic susceptibility and biofilm production of Staphylococcus aureus isolates recovered from bovine intramammary infections that persisted or not following extended therapies with cephapirin, pirlimycin or ceftiofur’, Veterinary Research, 48(1), p. 56. doi: 10.1186/s13567-017-0463-0.
Asli A, Brouillette E, Ster C, Ghinet MG, Brzezinski R, Lacasse P, Jacques M, Malouin F. (2017) ‘Antibiofilm and antibacterial effects of specific chitosan molecules on Staphylococcus aureus isolates associated with bovine mastitis’, PloS One, 12(5), p. e0176988. doi: 10.1371/journal.pone.0176988.
King AM, King DT, French S, Brouillette E, Asli A, Alexander JAN, Vuckovic M, Maiti SN, Parr TRJr, Brown ED, Malouin F Strynadka NCJ, Wright GD. (2016) ‘Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins’, ACS chemical biology, 11(4), pp. 864–868. doi: 10.1021/acschembio.5b00944.
Asli A, Brouillette E, Krause KM, Nichols WW, Malouin, F. (2016) ‘Distinctive Binding of Avibactam to Penicillin-Binding Proteins of Gram-Negative and Gram-Positive Bacteria’, Antimicrobial Agents and Chemotherapy, 60(2), pp. 752–756. doi: 10.1128/AAC.02102-15.
Goetz C, Dufour S, Archambault M, Malouin F, Jacques M. (2016) ‘intra-mammaires chez la vache laitière : une revue bibliographique’, Revue Méd. Vét., p. 14.
Côté-Gravel J, Brouillette E, Obradović N, Ster C, Talbot BG, Malouin F. (2016) ‘Characterization of a vraG Mutant in a Genetically Stable Staphylococcus aureus Small-Colony Variant and Preliminary Assessment for Use as a Live-Attenuated Vaccine against Intrammamary Infections’, PloS One, 11(11), p. e0166621. doi: 10.1371/journal.pone.0166621.
Boulanger S, Mitchell G, Bouarab K, Marsault É, Cantin A, Frost EH, Déziel E, Malouin F. (2015) ‘Bactericidal Effect of Tomatidine-Tobramycin Combination against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa Is Enhanced by Interspecific Small-Molecule Interactions’, Antimicrobial Agents and Chemotherapy, 59(12), pp. 7458–7464. doi: 10.1128/AAC.01711-15.
Daigle F, Lerat S, Bucca G, Sanssouci É, Smith CP, Malouin F, Beaulieu C. (2015) ‘A terD domain-encoding gene (SCO2368) is involved in calcium homeostasis and participates in calcium regulation of a DosR-like regulon in Streptomyces coelicolor’, Journal of Bacteriology, 197(5), pp. 913–923. doi: 10.1128/JB.02278-14.
Freschi L, Jeukens J, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Laroche J, Larose S. Maaroufi H. Fothergill JL, Moore M, Winsor GL, Aaron SD, Barbeau J, Bell SC, Burns JL, Camara M, Cantin A, Charette SJ, Dewar K, Déziel E, Grimwood K, Hancock RE, Harrison JJ, Heeb S., Jelsbak L, Jia B, Kenna DT, Kidd TJ, Klockgether J, Lam JS, Lamont IL, Lewenza S. Loman N, Malouin F, Manos J, McArthur AG, McKewown J, Milot J, Naghra H., Nguyen D, Pereira SK, Perron GG, Pirnay J-P, Rainey PB, Rousseau S, Santos PM, Stephenson A, Taylor V, Turton JF, Waglechner N, Williams P, Thrane SW, Wright GD, Brinkman FS, Tucker NP, Tümmler B, Winstanley C, Levesque RC. (2015) ‘Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium’, Frontiers in Microbiology, 6, p. 1036. doi: 10.3389/fmicb.2015.01036.
Klein RC, Fabres-Klein MH, de Oliveira LL, Feio RN, Malouin F, Ribon A de OB. (2015) ‘A C-type lectin from Bothrops jararacussu venom disrupts Staphylococcal biofilms’, PloS One, 10(3), p. e0120514. doi: 10.1371/journal.pone.0120514.
Veh KA, Klein RC, Ster C, Keefe G, Lacasse P, Scholl D, Roy J-P, Haine D, Dufour S, Talbot BG, Ribon AOB, Malouin F. (2015) ‘Genotypic and phenotypic characterization of Staphylococcus aureus causing persistent and nonpersistent subclinical bovine intramammary infections during lactation or the dry period’, Journal of Dairy Science, 98(1), pp. 155–168. doi: 10.3168/jds.2014-8044.
Chagnon F, Guay I, Bonin MA, Mitchell G, Bouarab K, Malouin F, Marsault E. (2014) ‘Unraveling the structure-activity relationship of tomatidine, a steroid alkaloid with unique antibiotic properties against persistent forms of Staphylococcus aureus’, European Journal of Medicinal Chemistry, 80, pp. 605–620. doi: 10.1016/j.ejmech.2013.11.019.
Diarra MS, Malouin F. (2014) ‘Antibiotics in Canadian poultry productions and anticipated alternatives’, Frontiers in Microbiology, 5, p. 282. doi: 10.3389/fmicb.2014.00282.
Fugère A, Lalonde Séguin D, Mitchell G, Déziel E, Dekimpe V, Cantin AM, Frost E, Malouin F. (2014) ‘Interspecific small molecule interactions between clinical isolates of Pseudomonas aeruginosa and Staphylococcus aureus from adult cystic fibrosis patients’, PloS One, 9(1), p. e86705. doi: 10.1371/journal.pone.0086705.
Gagnon H, Beauchemin S, Kwiatkowska A, Couture F, D’Anjou F, Levesque C, Dufour F, Roberge Desbiens A, Vaillancourt R, Bernard S, Desjardins R, Malouin F, Dory YL, Day R. (2014) ‘Optimization of Furin Inhibitors To Protect against the Activation of Influenza Hemagglutinin H5 and Shiga Toxin’, Journal of Medicinal Chemistry, 57(1), pp. 29–41. doi: 10.1021/jm400633d.
Simmons K, Rempel H, Block G, Forgetta V, Vaillancourt R, Malouin F, Topp E, Delaquis P, Diarra MS. (2014) ‘Duplex PCR methods for the molecular detection of Escherichia fergusonii isolates from broiler chickens’, Applied and Environmental Microbiology, 80(6), pp. 1941–1948. doi: 10.1128/AEM.04169-13.
Allard M, Ster C, Jacob CL, Scholl D, Diarra MS, Lacasse P, Malouin F. (2013) ‘The expression of a putative exotoxin and an ABC transporter during bovine intramammary infection contributes to the virulence of Staphylococcus aureus’, Veterinary Microbiology, 162(2–4), pp. 761–770. doi: 10.1016/j.vetmic.2012.09.029.
Diarra MS, Block G, Rempel H, Oomah BD, Harrison J, McCallum J, Boulanger S, Brouillette E, Gattuso M, Malouin F. (2013) ‘In vitro and in vivo antibacterial activities of cranberry press cake extracts alone or in combination with β-lactams against Staphylococcus aureus’, BMC complementary and alternative medicine, 13, p. 90. doi: 10.1186/1472-6882-13-90.
Fatima M, Rempel H, Kuang XT, Allen KJ, Cheng KM, Malouin F, Diarra MS. (2013) ‘Effect of 3’,5’-cyclic diguanylic acid in a broiler Clostridium perfringens infection model’, Poultry Science, 92(10), pp. 2644–2650. doi: 10.3382/ps.2013-03143.
Mitchell G, Fugère A, Pépin Gaudreau K, Brouillette E, Frost EH, Cantin AM, Malouin F. (2013) ‘SigB is a dominant regulator of virulence in Staphylococcus aureus small-colony variants’, PloS One, 8(5), p. e65018. doi: 10.1371/journal.pone.0065018.
Pariseau É, Massé DI, Masse L, Topp E, Burrus V., Malouin F. (2013) ‘Coagulation–flocculation pre-treatment of surface water used on dairy farms and evaluation of bacterial viability and gene transfer in treatment sludge’, Water Quality Research Journal, 48(2), pp. 111–120. doi: 10.2166/wqrjc.2013.140.
Ster C, Allard M, Boulanger S, Lamontagne Boulet M, Mulhbacher J, Lafontaine DA, Marsault É, Lacasse P, Malouin F. (2013) ‘Experimental treatment of Staphylococcus aureus bovine intramammary infection using a guanine riboswitch ligand analog’, Journal of Dairy Science, 96(2), pp. 1000–1008. doi: 10.3168/jds.2012-5890.
Forgetta V, Rempel H, Malouin F, Vaillancourt R, Topp E, Dewar K, Diarra MS. (2012) ‘Pathogenic and multidrug-resistant Escherichia fergusonii from broiler chicken’, Poultry Science, 91(2), pp. 512–525. doi: 10.3382/ps.2011-01738.
Mitchell G, Lafrance M, Boulanger S, Séguin DL, Guay I, Gattuso M, Marsault É, Bouarab K, Malouin F. (2012) ‘Tomatidine acts in synergy with aminoglycoside antibiotics against multiresistant Staphylococcus aureus and prevents virulence gene expression’, The Journal of Antimicrobial Chemotherapy, 67(3), pp. 559–568. doi: 10.1093/jac/dkr510.
Bordeleau E, Fortier L-C, Malouin F, Burrus V. (2011) ‘c-di-GMP turn-over in Clostridium difficile is controlled by a plethora of diguanylate cyclases and phosphodiesterases’, PLoS genetics, 7(3), p. e1002039. doi: 10.1371/journal.pgen.1002039.
Mitchell, G., Grondin, G., et al. (2011) ‘Infection of polarized airway epithelial cells by normal and small-colony variant strains of Staphylococcus aureus is increased in cells with abnormal cystic fibrosis transmembrane conductance regulator function and is influenced by NF-κB’, Infection and Immunity, 79(9), pp. 3541–3551. doi: 10.1128/IAI.00078-11.
Mitchell G, Gattuso M, Grondin G, Marsault É, Bouarab K, Malouin F. (2011) ‘Tomatidine inhibits replication of Staphylococcus aureus small-colony variants in cystic fibrosis airway epithelial cells’, Antimicrobial Agents and Chemotherapy, 55(5), pp. 1937–1945. doi: 10.1128/AAC.01468-10.
Pruneau M, Mitchell G, Moisan H, Dumont-Blanchette E, Jacob CL, Malouin F. (2011) ‘Transcriptional analysis of antibiotic resistance and virulence genes in multiresistant hospital-acquired MRSA’, FEMS immunology and medical microbiology, 63(1), pp. 54–64. doi: 10.1111/j.1574-695X.2011.00830.x.
Ster C, Beaudoin F, Diarra MS, Jacques M, Malouin F, Lacasse P. (2010) ‘Evaluation of some Staphylococcus aureus iron-regulated proteins as vaccine targets’, Veterinary Immunology and Immunopathology, 136(3–4), pp. 311–318. doi: 10.1016/j.vetimm.2010.03.010.
Lefebvre B, Diarra MS, Fairbrother JM, Nadeau E, Dubois M, Malouin F. (2010) ‘Intestinal mucosa adherence and cytotoxicity of a sorbitol-fermenting, Shiga-toxin-negative Escherichia coli O157:NM isolate with an atypical type III secretion system’, Foodborne Pathogens and Disease, 7(8), pp. 985–990. doi: 10.1089/fpd.2009.0474.
Mitchell G, Brouillette E, Séguin DL, Asselin A-E, Jacob CL, Malouin F. (2010) ‘A role for sigma factor B in the emergence of Staphylococcus aureus small-colony variants and elevated biofilm production resulting from an exposure to aminoglycosides’, Microbial Pathogenesis, 48(1), pp. 18–27. doi: 10.1016/j.micpath.2009.10.003.
Mitchell G, Séguin DL, Asselin A-E, Déziel E, Cantin AM, Frost EH, Michaud S, Malouin F. (2010) ‘Staphylococcus aureus sigma B-dependent emergence of small-colony variants and biofilm production following exposure to Pseudomonas aeruginosa 4-hydroxy-2-heptylquinoline-N-oxide’, BMC microbiology, 10, p. 33. doi: 10.1186/1471-2180-10-33.
Moisan H, Pruneau M, Malouin F. (2010) ‘Binding of ceftaroline to penicillin-binding proteins of Staphylococcus aureus and Streptococcus pneumoniae’, The Journal of Antimicrobial Chemotherapy, 65(4), pp. 713–716. doi: 10.1093/jac/dkp503.
Mulhbacher J, Brouillette E, Allard M, Fortier L-C, Malouin F, Lafontaine DA. (2010) ‘Novel riboswitch ligand analogs as selective inhibitors of guanine-related metabolic pathways’, PLoS pathogens, 6(4), p. e1000865. doi: 10.1371/journal.ppat.1000865.
Diarra MS, Giguère K, Malouin F, Lefebvre B, Bach S, Delaquis P, Aslam M, Ziebell KA, Roy G. (2009) ‘Genotype, serotype, and antibiotic resistance of sorbitol-negative Escherichia coli isolates from feedlot cattle’, Journal of Food Protection, 72(1), pp. 28–36. doi: 10.4315/0362-028x-72.1.28.
González-Lamothe R, Mitchell G, Gattuso M, Diarra MS, Malouin F, Bouarab K. (2009) ‘Plant antimicrobial agents and their effects on plant and human pathogens’, International Journal of Molecular Sciences, 10(8), pp. 3400–3419. doi: 10.3390/ijms10083400.
Lefebvre B, Gattuso M, Moisan H, Malouin F, Diarra MS. (2009) ‘Genotype comparison of sorbitol-negative Escherichia coli isolates from healthy broiler chickens from different commercial farms’, Poultry Science, 88(7), pp. 1474–1484. doi: 10.3382/ps.2008-00426.
Lefebvre B, Diarra MS, Vincent C, Moisan H, Malouin F. (2009) ‘Relative cytotoxicity of Escherichia coli O157:H7 isolates from beef cattle and humans’, Foodborne Pathogens and Disease, 6(3), pp. 357–364. doi: 10.1089/fpd.2008.0188.
Miller MJ, Zhu H, Xu Y, Wu C, Walz AJ, Vergne A, Roosenberg JM, Moraski G, Minnick AA, McKee-Dolence J, Hu J, Fennell K, Dolence EK, Dong L., Franzblau S, Malouin F, Möllmann U. (2009) ‘Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents’, Biometals: An International Journal on the Role of Metal Ions in Biology, Biochemistry, and Medicine, 22(1), pp. 61–75. doi: 10.1007/s10534-008-9185-0.
LeThanh BV, Lebeau CJ, Messier S, Malouin F, Scholl D. (2008) ‘Epidemiologic association of Staphylococcus aureus virulence markers with intramammary infection chronicity’, Lam, T. J. G. M. (ed.) Mastitis control: From science to practice: Proceedings of international conference 30 september - 2 October 2008 The Hague, the Netherlands. The Netherlands: Wageningen Academic Publishers. Page 167-174. doi: 10.3920/978-90-8686-649-6.
Atalla H, Gyles C, Jacob CL, Moisan H, Malouin F, Mallard B. (2008) ‘Characterization of a Staphylococcus aureus small colony variant (SCV) associated with persistent bovine mastitis’, Foodborne Pathogens and Disease, 5(6), pp. 785–799. doi: 10.1089/fpd.2008.0110.
Lefebvre B, Diarra MS, Moisan H, Malouin, F. (2008) ‘Detection of virulence-associated genes in Escherichia coli O157 and non-O157 isolates from beef cattle, humans, and chickens’, Journal of Food Protection, 71(9), pp. 1774–1784. doi: 10.4315/0362-028x-71.9.1774.
Mitchell G, Lamontagne C-A, Brouillette E, Grondin G, Talbot BG, Grandbois M, Malouin F. (2008) ‘Staphylococcus aureus SigB activity promotes a strong fibronectin-bacterium interaction which may sustain host tissue colonization by small-colony variants isolated from cystic fibrosis patients’, Molecular Microbiology, 70(6), pp. 1540–1555. doi: 10.1111/j.1365-2958.2008.06511.x.
Boulanger D, Brouillette E, Jaspar F, Malouin F, Mainil J, Bureau F, Lekeux P. (2007) ‘Helenalin reduces Staphylococcus aureus infection in vitro and in vivo’, Veterinary Microbiology, 119(2–4), pp. 330–338. doi: 10.1016/j.vetmic.2006.08.020.
Karaolis DKR, Means TK, Yang D, Takahashi M, Yoshimura T, Muraille E, Philpott D, Schroeder JT, Hyodo M, Hayakawa Y, Talbot BG, Brouillette, Malouin F. (2007) ‘Bacterial c-di-GMP is an immunostimulatory molecule’, Journal of Immunology (Baltimore, Md.: 1950), 178(4), pp. 2171–2181. doi: 10.4049/jimmunol.178.4.2171.
Mitchell G, Lamontagne C-A, Lebel R, Grandbois M, Malouin F. (2007) ‘Single-molecule dynamic force spectroscopy of the fibronectin-heparin interaction’, Biochemical and Biophysical Research Communications, 364(3), pp. 595–600. doi: 10.1016/j.bbrc.2007.10.034.
Allard M, Moisan H, Brouillette E, Gervais AL, Jacques M, Lacasse P, Diarra MS, Malouin F. (2006) ‘Transcriptional modulation of some Staphylococcus aureus iron-regulated genes during growth in vitro and in a tissue cage model in vivo’, Microbes and Infection, 8(7), pp. 1679–1690. doi: 10.1016/j.micinf.2006.01.022.
Lefebvre B, Malouin F, Roy G, Giguère K, Diarra MS. (2006) ‘Growth performance and shedding of some pathogenic bacteria in feedlot cattle treated with different growth-promoting agents’, Journal of Food Protection, 69(6), pp. 1256–1264. doi: 10.4315/0362-028x-69.6.1256.
Moisan H, Brouillette E, Jacob CL, Langlois-Bégin P, Michaud S, Malouin F. (2006) ‘Transcription of virulence factors in Staphylococcus aureus small-colony variants isolated from cystic fibrosis patients is influenced by SigB’, Journal of Bacteriology, 188(1), pp. 64–76. doi: 10.1128/JB.188.1.64-76.2006.
Bernier G, Girijavallabhan V, Murray A, Niyaz N, Ding P, Miller MJ, Malouin F. (2005) ‘Desketoneoenactin-siderophore conjugates for Candida: evidence of iron transport-dependent species selectivity’, Antimicrobial Agents and Chemotherapy, 49(1), pp. 241–248. doi: 10.1128/AAC.49.1.241-248.2005.
Brouillette E, Hyodo M, Hayakawa Y, Karaolis DKR, Malouin F. (2005) ‘3’,5’-cyclic diguanylic acid reduces the virulence of biofilm-forming Staphylococcus aureus strains in a mouse model of mastitis infection’, Antimicrobial Agents and Chemotherapy, 49(8), pp. 3109–3113. doi: 10.1128/AAC.49.8.3109-3113.2005.
Brouillette E, Grondin G, Talbo, BG, Malouin F. (2005) ‘Inflammatory cell infiltration as an indicator of Staphylococcus aureus infection and therapeutic efficacy in experimental mouse mastitis’, Veterinary Immunology and Immunopathology, 104(3–4), pp. 163–169. doi: 10.1016/j.vetimm.2004.11.006.
Brouillette E, Malouin F. (2005) ‘The pathogenesis and control of Staphylococcus aureus-induced mastitis: study models in the mouse’, Microbes and Infection, 7(3), pp. 560–568. doi: 10.1016/j.micinf.2004.11.008.
Lefebvre B, Diarra MS, Giguère K, Roy G, Michaud S, Malouin F. (2005) ‘Antibiotic resistance and hypermutability of Escherichia coli O157 from feedlot cattle treated with growth-promoting agents’, Journal of Food Protection, 68(11), pp. 2411–2419. doi: 10.4315/0362-028x-68.11.2411.
Malouin F, Brouillette E, Martinez A, Boyll BJ, Toth JL, Gage JL, Allen NE. (2005) ‘Identification of antimicrobial compounds active against intracellular Staphylococcus aureus’, FEMS immunology and medical microbiology, 45(2), pp. 245–252. doi: 10.1016/j.femsim.2005.04.003.
Brouillette E, Grondin G, Lefebvre C, Talbot B., Malouin F. (2004) ‘Mouse mastitis model of infection for antimicrobial compound efficacy studies against intracellular and extracellular forms of Staphylococcus aureus’, Veterinary Microbiology, 101(4), pp. 253–262. doi: 10.1016/j.vetmic.2004.04.008.
Brouillette E, Martinez A, Boyll BJ, Allen NE, Malouin, F. (2004) ‘Persistence of a Staphylococcus aureus small-colony variant under antibiotic pressure in vivo’, FEMS immunology and medical microbiology, 41(1), pp. 35–41. doi: 10.1016/j.femsim.2003.12.007.
Brouillette E, Talbot BG, Malouin F. (2003) ‘The fibronectin-binding proteins of Staphylococcus aureus may promote mammary gland colonization in a lactating mouse model of mastitis’, Infection and Immunity, 71(4), pp. 2292–2295. doi: 10.1128/iai.71.4.2292-2295.2003.